First, juice the prickly pear. Grab 2-3 layers of cheesecloth, place a few diced pieces of prickly pear in the cloth, wrap up tightly and squeeze over a small cup. 1 prickly pear should give you about 2 oz of juice, which is enough for 1 margarita.

To make the cocktail, combine the prickly pear juice, lime juice, agave, tequila, and Cointreau in a shaker. Add in a few ice cubes, and shake until well-combined.

Serve in a sugar-rimmed glass with crushed ice and a slice of prickly pear for garnish. Enjoy!